INSPPIRE diagnositc criteria for pediatric chronic pancreatitis (2018)

Calculator

When to use

Irreversible, structural changes in the pancreas such as diffuse or focal destruction, sclerosis, pancreatic duct abnormalities/obstruction)

Yes

Some periods of abdominal pain consistent with pancreatic origin or lipase or amylase ≥ 3 times the upper limit of normal

Yes

Evidence of exocrine pancreatic insufficiency

Yes

Evidence of endocrine pancreatic insufficiency

Yes

Calculation

Please enter all the required inputs.

The INSPPIRE diagnostic criteria for pediatric chronic pancreatitis (2018) is a clinical calculator specifically designed for the pediatric population. INSPPIRE stands for International Study Group of Pediatric Pancreatitis: In Search for a Cure. This scoring system is used to diagnose chronic pancreatitis in children, a condition characterized by inflammation of the pancreas that does not heal or improve, gets worse over time, and leads to permanent damage. The clinical utility of the INSPPIRE diagnostic criteria is to provide a standardized method for diagnosing chronic pancreatitis in children, which can be challenging due to the variability in symptoms and the lack of specific diagnostic tests. The criteria take into account various factors including abdominal pain, imaging findings, pancreatic function tests, and histology. There are no specific exclusion criteria for the use of the INSPPIRE diagnostic criteria. However, it is important to note that this scoring system is specifically designed for the pediatric population and may not be applicable or accurate in adults. Additionally, it should be used in conjunction with clinical judgment and not as a standalone diagnostic tool.

Reference

Cheryl E Gariepy, Melvin B Heyman, Mark E Lowe et al. Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group. J Pediatr Gastroenterol Nutr. 2017 Jan;64(1):95-103.

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