The Lille Model for Alcoholic Hepatitis is a prognostic tool specifically designed for patients with alcoholic hepatitis who are being treated with corticosteroids. This model aids clinicians in predicting the response to corticosteroid therapy and the likelihood of survival at six months. It incorporates variables such as age, albumin, bilirubin, creatinine, prothrombin time, and evolution of bilirubin at day 7 of treatment. The Lille Model is particularly useful in identifying patients who are not responding to corticosteroid therapy by day 7, allowing for early discontinuation of treatment and consideration of alternative therapies. It should not be used in patients with non-alcoholic causes of hepatitis or those not receiving corticosteroid treatment for alcoholic hepatitis.
Reference
Alexandre Louvet, Sylvie Naveau, Marcelle Abdelnour et al. The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids. Hepatology. 2007 Jun;45(6):1348-54.
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