The Milan criteria for liver transplantation help determine if a patient qualifies for liver transplant based on specific medical conditions. This evaluation considers three key factors related to liver tumors and cancer spread. Here's how it works:

The inputs involve checking if the following conditions are satisfied:

- Presence of a single liver tumor that is 5 cm or smaller, or the presence of two to three tumors, each no larger than 3 cm.
- Absence of vascular invasion, indicating the tumor has not spread into blood vessels.
- Absence of extrahepatic metastases, signifying that the cancer has not extended beyond the liver.

For each condition:

- Condition A is met if the tumor size and count criteria are satisfied.
- Condition B is met if there's no evidence of vascular invasion.
- Condition C is satisfied if there are no signs of cancer spreading beyond the liver.

The outcome is based on checking all these conditions:

- If all three conditions (A, B, and C) are true, the result is that the patient meets the criteria for liver transplantation.
- If even one condition is false, the criteria are not met, and the patient does not qualify under the Milan criteria for liver transplantation.

These criteria aim to identify patients with a favorable prognosis following liver transplantation, thus prioritizing those who are most likely to benefit from the procedure.

The Milan Criteria is a clinical scoring system used to determine eligibility for liver transplantation in patients with hepatocellular carcinoma (HCC). This criteria is specifically applicable to patients with HCC who are being considered for liver transplantation. 

The clinical utility of the Milan Criteria is to identify those patients who are likely to have the most favorable outcomes following liver transplantation. It is based on the size and number of liver tumors, with patients meeting the criteria having a single tumor less than or equal to 5 cm in diameter, or up to three tumors each less than or equal to 3 cm in diameter, and no evidence of macrovascular invasion or extrahepatic spread.

Exclusion criteria for the use of the Milan Criteria include patients with tumors larger than the specified size, more than three tumors, evidence of macrovascular invasion, or extrahepatic disease. These patients are considered to have a higher risk of recurrence post-transplantation and are typically not considered suitable candidates for liver transplantation.