Modified Sequential Organ Failure Assessment (mSOFA score)

The Modified Sequential Organ Failure Assessment, abbreviated as mSOFA score, is a clinical calculator used primarily in the intensive care unit (ICU) setting. It is designed to quantify the severity and prognosis of critically ill patients, particularly those with suspected or confirmed sepsis. The mSOFA score assesses six organ systems: respiratory, coagulation, liver, cardiovascular, central nervous system, and renal. Each system is scored from 0 (normal) to 4 (high degree of dysfunction), with the total score ranging from 0 to 24. Higher scores indicate more severe organ dysfunction and a worse prognosis. The mSOFA score is applicable to adult patients in the ICU, especially those with sepsis. It is not typically used in pediatric populations or in patients with conditions that may confound the assessment of organ function, such as chronic liver disease or end-stage renal disease. The mSOFA score is a valuable tool for risk stratification, guiding therapeutic decisions, and predicting patient outcomes in the ICU.

Reference

Colin K Grissom, Samuel M Brown, Kathryn G Kuttler et al. A modified sequential organ failure assessment score for critical care triage. Disaster Med Public Health Prep. 2010 Dec;4(4):277-84.