Famotidine
Oral
Intravenous
Class
Acid suppression agents
Subclass
H2-antihistamines
Substance name
Famotidine
Brand names
Pepcid®
Common formulations
Film-coated tablet
Dosage and administration
Adults patients
Symptomatic relief
Dyspepsia
Treatment
Gastric hypersecretory conditions
GERD • Erosive
GERD • Nonerosive
Peptic ulcer disease • Gastric
Peptic ulcer disease • Duodenal
Laryngopharyngeal reflux • Off-label
Prevention
NSAID-induced peptic ulcer • Off-label
Stress ulcer • Off-label
Secondary prevention
Secondary prevention of peptic ulcer disease • Duodenal
Indications for use
Labeled indications
Adults
Children
Off-label indications
Adults
Safety risks
Contraindications
Hypersensitivity to famotidine or its components or other H2RAs
Warnings and precautions
CNS adverse events
Mask symptoms of gastric cancer
Specific populations
Renal impairment
GFR > 50 mL/min
CrCl 10-50 mL/min
CrCl < 10 mL/min
Renal replacement therapy
Continuous renal replacement
Intermittent hemodialysis
Peritoneal dialysis
Hepatic impairment
Any severity
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: B1
Breastfeeding
Acceptable for use during breastfeeding.
Unknown drug levels in breastfed infants.
Some adverse effects on lactation reported.
Adverse reactions
Common 1-10%
Uncommon < 1%
Unknown frequency
Interactions
Drug(s)
Check Interactions
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